Sexual Function

Medical Studies on DHEA – Sexual Function

DHEA Female Sexual Function

As a precursor hormone of estrogen and testosterone, DHEA plays an important role in healthy sexual function, in women and men. Vaginal dryness or pain during sex are often accompanying symptoms of menopause that can be treated well with DHEA. In men, androgens, including DHEA, are responsible for maintaining hormonal balance and healthy functioning of muscle, the prostate and the testes.

Intravaginal DHEA in Dyspareunia

Dyspareunia is a primary symptom of the genitourinary syndrome of menopause (GSM). This is a chronic, progressive condition that results from estrogen and androgen deficiency during menopause. The decrease in sex hormones at this stage of life contributes to a decrease in vaginal elasticity and lubricity, resulting in pain and dryness during intercourse. Intravaginal DHEA, applied as a cream, provides positive results, promoting hydration, helping to restore a fulfilling sex life and thus significantly improving quality of life. Systemic intake in physiological dosages can also help to correct the dysregulation of estrogen, testosterone and DHEA, contributing to the treatment of dyspareunia.

Maintaining a Healthy Erection

The causes of male potency concerns are many and varied. Above all, they include testosterone deficiency, circulatory disorders (often caused by high blood pressure), vascular concerns and diabetes mellitus, as well as obesity, neurological disorders, stress and depression. These are all risk factors that are intensified by a DHEA deficiency and are therefore also easy to treat. In addition, DHEA activates nitric oxide, which plays an extremely important role during sexual intercourse. This is because it influences vasocongestion, the regulation of vascular diameter which is the limiting factor that controls the swelling and contraction of the penis.

Medical Studies on DHEA – Sexual Function

Correction to: Dehydroepiandrosterone Sulphate (DHEAS) concentrations stringently regulate fertilization, embryo development and IVF outcomes: are we looking at a potentially compelling ‘oocyte-related factor’ in oocyte activation?

2021-05 Chimote BN, Chimote NM

Erratic oocyte-activation affects fertilization and embryo development. Dehydro-epiandrosterone sulphate (DHEAS) is present in theca/cumulus-granulosa cells, regulates the same calcium-pumps that cause calcium-oscillations in mice and its levels are altered in women with no or low fertilization rates. Yet no study has explored correlation of DHEAS with oocyte-activation.

Associations between androgens and sexual function in premenopausal women: a cross-sectional study

2020-08 Zheng J, Islam RM, Skiba MA, Bell RJ, Davis SR

Although clinicians often measure the serum concentration of androgens in premenopausal women presenting with sexual dysfunction, with some women given testosterone or dehydroepiandrosterone as treatment if their concentrations are low, whether androgens are determinants of sexual function in women of reproductive age is uncertain. We aimed to clarify the associations between androgens and sexual function in a community-based sample of non-health-care-seeking women.

Supplementation of dehydroepiandrosterone (DHEA) in pre- and postmenopausal women – position statement of expert panel of Polish Menopause and Andropause Society

2020-01 Rabijewski M, Papierska L, Binkowska M, Maksym R, Jankowska K, Skrzypulec-Plinta W, Zgliczynski W

Dehydroepiandrosterone (DHEA) concentration decreases with age, therefore, DHEA has been considered a hormone that reduces the symptoms associated with aging, so the usefulness of DHEA in premenopausal and postmenopausal women, and the options of hormone therapy have received a large amount of attention.

Dehydroepiandrosterone secretion in healthy older men and women: effects of testosterone and growth hormone administration in older men

2006-11 Muniyappa R, Wong KA, Baldwin HL, Sorkin JD, Johnson ML, Bhasin S, Harman SM, Blackman MR

Aging is associated with diminished gonadal steroid and GH/IGF-I axis activity; whether these changes contribute to the parallel declines of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) production is unknown, as are the effects of sex steroid and/or GH administration on DHEA and DHEAS production.

Dehydroepiandrosterone (DHEA) as a possible source for estrogen formation in bone cells: correlation between bone mineral density and serum DHEA-sulfate concentration in postmenopausal women, and the presence of aromatase to be enhanced by 1,25-dihydroxyvitamin D3 in human osteoblasts

2002-04 Takayanagi R, Goto K, Suzuki S, Tanaka S, Shimoda S, Nawata H

A significant positive correlation between bone mineral density (BMD) and serum dehydroepiandrosterone sulfate (DHEA-S) was found in 120 postmenopausal women (51–99 years old) but no correlation was seen between BMD and serum estradiol.

Scroll to Top